FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\ClkΔ657-707.Tag:V5
Open Close
General Information
Symbol
Dmel\ClkΔ657-707.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0325568
Feature type
allele
Associated gene
Dmel\Clk
Associated Insertion(s)
Carried in Construct
PBac{Clk.Δ657-707.V5}
Key Links
Transgenic product class
inframe_deletion
(Lee et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Lee et al., 2016)
Mutagen
in vitro construct
(Lee et al., 2016)
Progenitor genotype
Carried in construct
PBac{Clk.Δ657-707.V5}
Cytology
Description

Deletion of amino acids 657-707 (apparently important for per interaction and transcriptional activation) from a Clk genomic fragment, tagged with Tag:V5.

(Lee et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
Clk
Encoded product / tool
Clk
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Clkout homozygotes bearing ClkΔ657-707.Tag:V5 kept under constant darkness and subject to 12h:12h 24[o] C:29 [o]C temperature cycles exhibit bimodal peaks of activity with an increase in anticipatory activity before temperature transitions; upon transfer to constant 24[o]C, these individuals maintain some rhythmicity and manifest a 24.9h period.

      (Lee et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      ClkΔ657-707.Tag:V5 fails to rescue Clkout

      (Lee et al., 2016)
      Comments

      ClkΔ657-707.Tag:V5 rescues the circadian rhythm defects observed in Clkout homozygous adults.

      (Lee et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ClkΔ657-707.T:SV5\V5
      ClkΔ657-707.Tag:V5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)