FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\egrUAS.Venus
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General Information
Symbol
Dmel\egrUAS.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0325733
Feature type
allele
Associated gene
Dmel\egr
Associated Insertion(s)
Carried in Construct
P{UAS-egr.Venus}
Also Known As
UAS-Egr-venus
Key Links
Transgenic product class
wild_type
(Parisi et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Parisi et al., 2014)
Mutagen
in vitro construct
(Parisi et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-egr.Venus}
Cytology
Description

UAS regulatory sequences drive the expression of egr tagged with Venus.

(Parisi et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
egr
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  cancer
      modeled by dlg1A40.2
      (Parisi et al., 2014)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of egrUAS.Venus under the control of Scer\GAL4sd-SG29.1 leads to a smaller wing disc, as compared to controls. Expression under the control of Scer\GAL4Hml.Δ, however, does not have an obvious effect on the growth, patterning and apoptosis levels (cleaved caspase 3 immunostaining) in the wing disc, which is in agreement with a normal adult wing, as compared to controls

      (Parisi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4Hml.Δ/egrUAS.Venus is a suppressor | partially of wing disc phenotype of dlg1A40.2

      (Parisi et al., 2014)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of egrUAS.Venus under the control of Scer\GAL4r4 in a Alg3tid1/Alg3tid2 transheterozygous background leads to an increase in cell death (DCP-1-positive cells) in the wing disc, as compared to controls.

      (de Vreede et al., 2018)

      The apoptosis observed in dlg1A40.2 mutant wing disc tumors is significantly increased by the expression of egrUAS.Venus under the control of the Scer\GAL4Hml.Δ driver.

      (Parisi et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      egrScer\UAS.T:Avic\GFP-YFP.Venus
      egrUAS.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (4)