FlyBase Allele Report: Dmel\otk[HMS05827]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\otk^HMS05827

General Information

Symbol

Dmel\otk^HMS05827

Species

D. melanogaster

Name

FlyBase ID

FBal0326092

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS05827}

Key Links

Genomic Maps

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMS05827}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

ventral denticle belt | embryonic stage, with Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32

(Tan et al., 2024)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scer\GAL4^elav-C155, otk2^HMC04171, otk^HMS05827 has abnormal neuroanatomy | embryonic stage phenotype

(Tan et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32, otk^HMS05827 has ventral denticle belt | embryonic stage | ectopic phenotype, non-enhanceable by Wnt4^JF03378/Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32

(Tan et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32, otk^HMS05827 has ventral denticle belt | ectopic | embryonic stage phenotype, non-suppressible by Wnt4^JF03378/Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32

(Tan et al., 2024)

Other

Statement

Reference

Scer\GAL4^{VP16.mat.αTub67C}, Scer\GAL4^da.G32, otk2^HMC04171, otk^HMS05827 has ventral denticle belt | ectopic | embryonic stage phenotype

(Tan et al., 2024)

Scer\GAL4^elav-C155, otk2^HMC04171, otk^HMS05827 has larval nervous system | embryonic stage phenotype

(Tan et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

67966

y¹ sc^* v¹ sev²¹; P{TRiP.HMS05827}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

otk^HMS05827

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections