FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cnx99AUAS.Tag:FLAG
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General Information
Symbol
Dmel\Cnx99AUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0326605
Feature type
allele
Associated gene
Dmel\Cnx99A
Associated Insertion(s)
Carried in Construct
P{UAS-Cnx99A.3xFlag}
Key Links
Transgenic product class
cDNA
(Xiao et al., 2017)
wild_type
(Xiao et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Xiao et al., 2017)
wild_type
(Xiao et al., 2017)
Mutagen
in vitro construct
(Xiao et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Cnx99A.3xFlag}
Cytology
Description

UAS regulatory sequences drive expression of full-length Cnx99A (derived from the SD17909 cDNA clone), tagged with three copies of Tag:FLAG.

(Xiao et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cnx99A
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Cnx99AScer\UAS.T:Zzzz\FLAG alone under the control of Scer\GAL4elav.PU does not significantly affect the locomotor capacity of adults in negative geotaxis assays, as compared to controls.

      (Xiao et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of Cnx99AScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4sca.PU does not significantly suppress the paralysis phenotype of parats1 homozygotes induced by temperature shift to 38[o]C, as shown by a similar recovery from paralysis upon return to room temperature.

      (Xiao et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav.PU/Cnx99AUAS.Tag:FLAG partially rescues Cnx99A2

      (Xiao et al., 2017)

      Scer\GAL4elav.PU/Cnx99AUAS.Tag:FLAG partially rescues Cnx99AKK108301

      (Xiao et al., 2017)
      Comments

      The expression of Cnx99AScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU partially rescues the adult locomotion defects observed in Cnx99A2 homozygotes or upon expression of Cnx99AKK108301 under the combined control of Scer\GAL4elav.PU and Dicer-2 transgene.

      (Xiao et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cnx99AScer\UAS.T:Zzzz\FLAG
      Cnx99AUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)