FB2026_02 , released June 18, 2026
Allele: Dmel\Sec71Ex11
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General Information
Symbol
Dmel\Sec71Ex11
Species
D. melanogaster
Name
FlyBase ID
FBal0326751
Feature type
allele
Associated gene
Dmel\Sec71
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Wang et al., 2017)
Progenitor genotype
P{GSV6}Sec71GS16990
(Wang et al., 2017)
Cytology
Description

1461bp deletion within Sec71.

(Wang et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Clonal Sec71Ex11-homozygous dorsal multidendritic ddaC neurons within a mosaic individual exhibit a significantly simplified dendritic arborization at the white pupa stage and pruning defects, as shown by the persistence of some branches at 16h-18h after puparium formation, as compared to controls.

      (Wang et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Sec71Ex11 is rescued by Scer\GAL4elav.PU/Sec71UAS.RR

      (Wang et al., 2017)
      Comments

      The defects in dendrite pruning at 16h after puparium formation observed in clonal Sec71Ex11-homozygous dorsal multidendritic ddaC neurons is rescued by the clonal expression of Sec71Scer\UAS.RNAi-resistant under the control of Scer\GAL4elav.PU.

      (Wang et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Sec71Ex11
      (Gujar et al., 2025, Wang et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)