FB2026_03 , released September 17, 2026
Allele: Dmel\Mettl14SK2
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General Information
Symbol
Dmel\Mettl14SK2
Species
D. melanogaster
Name
FlyBase ID
FBal0327398
Feature type
allele
Associated gene
Dmel\Mettl14
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Kan et al., 2017)
Mutagen
CRISPR/Cas9
(Kan et al., 2017)
Progenitor genotype
Cytology
Description

A frameshift indel in the second exon (coding region) expected to produce a non-functional protein.

(Kan et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2L:8,308,908..8,308,917 [+]
Comment:

Deletion of 10 nucleotides and insertion of 6 nucleotides (GTTCTG) leads to a net deletion of 4 bases causing a frameshift after amino acid 97 and early translation termination after the addition of 12 novel amino acids.

Inserted_sequence:

GTTCTG

(Kan et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mettl14SK2
      mettl14SK2
      (Kan et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)