FB2026_02 , released June 18, 2026
Allele: Dmel\torDeg
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General Information
Symbol
Dmel\torDeg
Species
D. melanogaster
Name
FlyBase ID
FBal0327520
Feature type
allele
Associated gene
Dmel\tor
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Pae et al., 2017)
Progenitor genotype
Cytology
Description

tor mutant that carries alanines in lieu of the degron motif (to disrupt interaction with gcl).

(Pae et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2R:7,706,410..7,706,424 [-]
Comment:

Amino acids IENIG (649-653 in tor-PA) were mutated to a series of alanines (IENIG>5A).

Inserted_sequence:

GCNGCNGCNGCNGCN

(Pae et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos from torDeg/tor2 transheterozygous mothers display a severe failure in primordial germ cell formation, as compared to controls.

      (Pae et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      torDeg
      torsoDeg
      (Pae et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)