FB2026_02 , released June 18, 2026
Allele: Dmel\Sarm4314
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General Information
Symbol
Dmel\Sarm4314
Species
D. melanogaster
Name
FlyBase ID
FBal0327551
Feature type
allele
Associated gene
Dmel\Sarm
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Neukomm et al., 2017)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      axed0011

      (Neukomm et al., 2017)

      axed2094

      (Neukomm et al., 2017)
      Fails to complement

      Sarm896

      (Neukomm et al., 2017)
      Rescued by

      Sarm4314 is rescued by Sarm+tOa

      (Neukomm et al., 2017)
      Comments

      Ect44314 fails o complement the lethality of Ect4896 but complements lethality of axed2094 and axed0011.

      The axon death defect (severed axons remain intact for a full week after an axotomy, instead of being cleared away by day 5) characteristic for Ect44314 mutants is rescued by combination with Ect4+tOa.

      (Neukomm et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      3L.4314
      (Neukomm et al., 2017)
      Ect44314
      Sarm4314
      dsarm4314
      (Neukomm et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)