FlyBase Allele Report: Dmel\Arf1[182-1]

General Information

Symbol

Dmel\Arf1^182-1

Species

D. melanogaster

Name

FlyBase ID

FBal0328047

Feature type

allele

Associated gene

Dmel\Arf1

Associated Insertion(s)

Carried in Construct

Also Known As

arf79F^182-1

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(West et al., 2017)

Mutagen

Delta2-3 transposase

(West et al., 2017)

Progenitor genotype

P{EPgy2}Arf1^EY08473

(West et al., 2017)

Cytology

Description

Imprecise excision of P{EPgy2}Arf79F^EY08473 results in deletion of the Arf79F protein coding sequence.

(West et al., 2017)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

During mid-dorsal closure, Arf79F^182-1 homozygous embryos exhibit no obvious epidermal defects, as shown by the insignificant differences in the frequency of rosette-like structures, as compared to controls.

(West et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Arf1^182-1, Arf6^KO has abnormal cell shape phenotype

(West et al., 2017)

Phenotype Manifest In

Enhancer of

Statement

Reference

Arf1^182-1/Arf79F[+] is an enhancer of wing hair | ectopic phenotype of arm^Ndel.vg.MQ

(Marcetteau et al., 2021)

Arf1^182-1/Arf79F[+] is an enhancer of mechanosensory medial triple row bristle | decreased number phenotype of Arf6¹

(Marcetteau et al., 2021)

Arf1^182-1/Arf79F[+] is an enhancer of mechanosensory medial triple row bristle | decreased number phenotype of Arf6^GX16w-

(Marcetteau et al., 2021)

Other

Statement

Reference

Arf1^182-1, Arf6^KO has embryonic epidermis phenotype

(West et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

During mid-dorsal closure, Arf79F^182-1, Arf51F^KO double homozygous embryos exhibit no obvious epidermal defects, as shown by the insignificant differences in the frequency of rosette-like structures, as compared to single homozygous mutants.

(West et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Arf1^182-1

Arf79F^182-1

(Zeledon et al., 2019)

arf1^182-1

(Marcetteau et al., 2021)

arf79F^182-1

(Marcetteau et al., 2021, West et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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