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General Information
Symbol
Hsap\RELAAD.R21F05
Species
H. sapiens
Name
FlyBase ID
FBal0328516
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
R21F05
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The GMR21F05 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the p65(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the p65 activation domain).

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
descending neuron of the anterior ventral brain DNb02

Comment: when combined with P{R93B10-GAL4.DBD} (combination referred to as 'SS02396')

Additional Information
Statement
Reference

Hsap\RELAAD.R21F05 expression when combined with Scer\GAL4DBD.R21H11 is stochastic in descending neuron of the anterior ventral brain DNb02.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Acute, high intensity optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 617 nm (red) light) of neurons targeted by the split-GAL4 pair of Scer\GAL4DBD.R58E05 and Hsap\RELAAD.R21F05 in larvae induces contraction of transverse muscle LT2, but not longitudinal muscle LO1, compared to baseline; chronic, low-level stimulation causes transverse muscle LT2 to contract earlier than normal in the locomotor cycle, reducing the phase offset between LT2 and LO1 contractions, compared to baseline.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Hsap\RELAAD.R21F05.T:Zzzz\Zip+
Hsap\RELAAD.R21F05
Name Synonyms
Secondary FlyBase IDs
    References (5)