FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Piezo-MI04189-TG4.0
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General Information
Symbol
Scer\GAL4Piezo-MI04189-TG4.0
Species
S. cerevisiae
Name
FlyBase ID
FBal0336206
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Mi{Trojan-GAL4.0}PiezoMI04189-TG4.0
Carried in Construct
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Gene Disruption Project members, 2016-)
Progenitor genotype
Associated Insertion(s)
Mi{Trojan-GAL4.0}PiezoMI04189-TG4.0
Cytology
Description

The RMCE cassette of the Mi{MIC}PiezoMI04189 insertion has been replaced with a Trojan-GAL4 cassette. The insertion is in a coding intron of Piezo and is predicted to gene trap the gene. (Note that if this gene has multiple transcripts, only those where the insertion is in a coding intron are predicted to be trapped).

(Gene Disruption Project members, 2016-)
Allele components
Component
Use(s)
Inserted element
Mi{Trojan-GAL4.0}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The acute inhibition of Piezo-positive neurons, by expressing shi1.UAS under the control of Scer\GAL4Piezo-MI04189-TG4.0 and testing adults at the non-permissive 32[o]C) increases feeding (also leading to gut bloating and increased crop size). Conversely, acute activation of Piezo-positive neurons, by expressing TrpA1UAS.(B).cKa under the control of Scer\GAL4Piezo-MI04189-TG4.0 and activating it 30[o]C suppresses feeding (and crop size).

      (Min et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Piezo-MI04189-TG4.0
      Name Synonyms
      Secondary FlyBase IDs
        References (3)