FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Balat1
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General Information
Symbol
Dmel\Balat1
Species
D. melanogaster
Name
FlyBase ID
FBal0336280
Feature type
allele
Associated gene
Dmel\Balat
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Han et al., 2017)
Mutagen
CRISPR/Cas9
(Han et al., 2017)
Progenitor genotype
Cytology
Description

Deletion of ~900bp of the Balat locus, including parts of coding exons 2 and 3.

(Han et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Balat1 homozygosity virtually abolishes the normal electroretinogram ON and OFF transients upon light stimulation and severely impairs visual perception, as assessed by phototaxis assays, as compared to controls.

      (Han et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Balat1 is rescued by BalatPdh.PH

      (Han et al., 2017)

      Balat1 is rescued by BalatGMR.PH

      (Han et al., 2017)
      Comments

      Both the lack of electroretinogram ON and OFF transients upon light stimulation and the severely decreased phototaxis presented by Balat1 homozygous adults are rescued by BalatPdh.PH. The severely decreased phototaxis presented by Balat1 homozygous adults is also rescued by BalatGMR.PH.

      (Han et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Balat1
      balat1
      (Han et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)