FB2026_02 , released June 18, 2026
Allele: Dmel\Balat2
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General Information
Symbol
Dmel\Balat2
Species
D. melanogaster
Name
FlyBase ID
FBal0336281
Feature type
allele
Associated gene
Dmel\Balat
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Han et al., 2017)
Mutagen
CRISPR/Cas9
(Han et al., 2017)
Progenitor genotype
Cytology
Description

Deletion of ~660bp of the Balat locus, including parts of coding exons 3 and 4.

(Han et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Balat2 homozygosity virtually abolishes the normal electroretinogram ON and OFF transients upon light stimulation, as compared to controls.

      Balat2 homozygous adults bearing BalatninaE.PH present a severely impaired visual perception, as assessed by phototaxis assays, as compared to controls.

      (Han et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Not rescued by

      Balat2 is not rescued by BalatninaE.PH

      (Han et al., 2017)
      Comments

      The lack of electroretinogram ON transients upon light stimulation presented by Balat2 homozygous adults are not rescued by BalatninaE.PH.

      (Han et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Balat2
      balat2
      (Han et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)