FB2026_02 , released June 18, 2026
Allele: Dmel\Rexo5H493R.UAS
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General Information
Symbol
Dmel\Rexo5H493R.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0336306
Feature type
allele
Associated gene
Dmel\Rexo5
Associated Insertion(s)
Carried in Construct
P{UAS-Rexo5.H493R}
Key Links
Transgenic product class
missense_variant
(Gerstberger et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Gerstberger et al., 2017)
Mutagen
in vitro construct
(Gerstberger et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Rexo5.H493R}
Cytology
Description

UAS regulates expression of Rexo5 containing a H493R substitution.

(Gerstberger et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rexo5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Act.PU/Rexo5H493R.UAS partially rescues Rexo5c04255

      (Gerstberger et al., 2017)

      Scer\GAL4Act.PU/Rexo5H493R.UAS partially rescues Rexo5E497K

      (Gerstberger et al., 2017)
      Comments

      The second larval instar lethality of either Rexo5c04255 or Rexo5E497K homozygotes is only partially rescued by Scer\GAL4Act.PU-driven expression of Rexo5H493R.Scer\UAS as the larvae survive until the third instar stage.

      (Gerstberger et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rexo5H493R.Scer\UAS
      Rexo5H493R.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)