FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Myd88cr2.8
Open Close
General Information
Symbol
Dmel\Myd88cr2.8
Species
D. melanogaster
Name
FlyBase ID
FBal0337125
Feature type
allele
Associated gene
Dmel\Myd88
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Foldi et al., 2017)
Mutagen
CRISPR/Cas9
(Foldi et al., 2017)
Progenitor genotype
Cytology
Description

7bp deletion that causes a frame-shift at amino acid 64 and a premature stop codon at amino acid 94.

(Foldi et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:9,307,599..9,307,605 [-]
Comment:

A 7 bp deletion that causes a frameshift at amino acid 64 and early translation termination after the addition of 32 novel amino acids.

(Foldi et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Myd88cr2.8/Df(2R)BSC279 mutant pupae display a moderate decrease in the number of eve-positive neurons and a significant increase in the number of apoptotic (Dcp-1-positive) cells in pupal ventral nerve cord.

      (Foldi et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MyD88cr2.8
      (Foldi et al., 2017)
      Myd88cr2.8
      Name Synonyms
      Secondary FlyBase IDs
        References (1)