FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4ths-MI07139-TG4.1
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General Information
Symbol
Scer\GAL4ths-MI07139-TG4.1
Species
S. cerevisiae
Name
FlyBase ID
FBal0337143
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Mi{Trojan-GAL4.1}thsMI07139-TG4.1
Carried in Construct
Also Known As
ths-GAL4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Wu et al., 2017)
Progenitor genotype
Mi{MIC}thsMI07139
(Wu et al., 2017)
Associated Insertion(s)
Mi{Trojan-GAL4.1}thsMI07139-TG4.1
Cytology
Description

The RMCE cassette of the Mi{MIC}thsMI07139 insertion has been replaced with a Trojan-GAL4 cassette, allowing expression of Scer\GAL4 under the control of endogenous ths regulatory sequences.

(Wu et al., 2017)
Allele components
Component
Use(s)
Inserted element
Mi{Trojan-GAL4.1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      mesothoracic tergum primordium
      (Patel et al., 2022)
      adult stage
      projection neuron | subset
      (Wu et al., 2017)
      adult olfactory receptor neuron | subset
      (Wu et al., 2017)
      interneuron | subset
      (Wu et al., 2017)
      Additional Information
      Statement
      Reference

      In a FLP based system, ScerGAL4ths-MI07139-TG4.1 drives expression in 19 projection neurons when combined with ScerFLP1o.GH146.PP, and in adult olfactory receptor neurons when combined with ScerFLP1ey.PN. In a GAL80 based system, expression is seen in approximately 27 intrinsic neurons when combined with ScerGAL80GH146.PP.

      (Wu et al., 2017)
       
      Marker for
      Reflects expression of
      ths
      (Patel et al., 2022, Wu et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4ths-MI07139-TG4.1
      thsMI07139-TG4.1
      (Lei et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)