FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\zldJAZ
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General Information
Symbol
Dmel\zldJAZ
Species
D. melanogaster
Name
FlyBase ID
FBal0337846
Feature type
allele
Associated gene
Dmel\zld
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Hamm et al., 2017)
Progenitor genotype
Cytology
Description

Amino acid replacement: F561A.

(Hamm et al., 2017)

Point mutations within Zinc Finger 2.

(Hamm et al., 2017)

Amino acid replacement: S563A.

(Hamm et al., 2017)

Amino acid replacement: Y571A.

(Hamm et al., 2017)

Amino acid replacement: N578A.

(Hamm et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
X:19,780,605..19,780,606 [-]
Nucleotide change:

TT19780606GC

Reported nucleotide change:

TT?GC

Reported amino acid change:

F561A

Comment:

zld codon 561 was changed from TTC to GCC (F561A). (A typo in Fig. 5 shows codon 561 as GTC instead of TTC but refers to is as aa F561).

(Hamm et al., 2017)
MNV
X:19,780,599..19,780,600 [-]
Nucleotide change:

AG19780600GC

Reported nucleotide change:

AG?GC

Reported amino acid change:

S563A

Comment:

Codon 563 was changed from AGC to GCC (S563A).

(Hamm et al., 2017)
MNV
X:19,780,575..19,780,576 [-]
Nucleotide change:

TA19780576GC

Reported nucleotide change:

TA?GC

Reported amino acid change:

Y571A

Comment:

Codon 571 was changed from TAC to GCC (Y571A).

(Hamm et al., 2017)
MNV
X:19,780,553..19,780,555 [-]
Nucleotide change:

AAT19780555GCC

Reported nucleotide change:

AAT?GCC

Reported amino acid change:

N578A

Comment:

Codon 578 was changed from AAT to GCC (N578A).

(Hamm et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      zldJAZ homozygous females and hemizygous males are partially viable at much reduced levels but the females are sterile. zld294/zldJAZ females are nearly completely lethal.

      (Hamm et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      zldJAZ
      (Hamm et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)