FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rtnl1+tCH322-124P15
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General Information
Symbol
Dmel\Rtnl1+tCH322-124P15
Species
D. melanogaster
Name
FlyBase ID
FBal0338075
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

Genomic fragment (Pacman BAC clone CH322-124P15) that includes Rtnl1.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

Genomic fragment (Pacman BAC clone CH322-124P15) that includes Rtnl1 used as rescue fragment.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

The frequency of gaps in the axonal endoplasmic reticulum observed in Rtnl11.W mutant third instar larvae is somewhat decreased by combination with Rtnl1+tCH322-124P15 but still above that seen in control larvae.

Combination with two copies of Rtnl1+tCH322-124P15 rescues the abnormal accumulations of synaptic vesicle protein Csp, used as a read-out for axonal transport, detected in Rtnl11.W,ReepB48;ReepA541 triple mutant third instar larvae.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Rtnl1+tCH322-124P15
Name Synonyms
Secondary FlyBase IDs
    References (1)