Genomic fragment (Pacman BAC clone CH322-124P15) that includes Rtnl1.
Genomic fragment (Pacman BAC clone CH322-124P15) that includes Rtnl1 used as rescue fragment.
Rtnl1+tCH322-124P15 partially rescues Rtnl11.W
The frequency of gaps in the axonal endoplasmic reticulum observed in Rtnl11.W mutant third instar larvae is somewhat decreased by combination with Rtnl1+tCH322-124P15 but still above that seen in control larvae.
Combination with two copies of Rtnl1+tCH322-124P15 rescues the abnormal accumulations of synaptic vesicle protein Csp, used as a read-out for axonal transport, detected in Rtnl11.W,ReepB48;ReepA541 triple mutant third instar larvae.