FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Obp28adel
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General Information
Symbol
Dmel\Obp28adel
Species
D. melanogaster
Name
FlyBase ID
FBal0338099
Feature type
allele
Associated gene
Dmel\Obp28a
Associated Insertion(s)
TI{TI}Obp28adel
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Larter et al., 2016)
Mutagen
CRISPR/Cas9
(Larter et al., 2016)
Progenitor genotype
Associated Insertion(s)
TI{TI}Obp28adel
Cytology
Description

The coding sequences of Obp28a have been deleted and replaced with sequence comprising a loxP-flanked 3xP3-DsRed(T1) marker plus an attP site.

(Larter et al., 2016)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2L:7,496,861..7,497,310 [-]
Comment:

Most of the coding sequence of Obp28a has been deleted and replaced with a dsRed cassette and an attP PhiC31 site.

(Larter et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Similarly to controls, Obp28adel homozygous adults placed in a space with two separate regions of high and low humidity show the expected hygrotaxis behavior towards the higher humidity region. These flies also do not show significant defects in survival under desiccation or 70% humidity conditions, as compared to controls.

      (Sun et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Obp19adel, Obp28adel has antennal basiconic sensillum ab4 | chemical conditional phenotype

      (Xiao et al., 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Obp28adel and Obp19adel homozygous mutant adults do not have gross defects in the size, morphology or position of basiconic sensilla, compared to controls; mutant ab5 and ab6 sensilla have no difference in their responses to odorants, compared to controls; mutant ab4 sensilla have stronger responses to linoleic acid, but not other odorants, and females have a shifted preference for oviposition on lower concentrations of linoleic acid, compared to controls.

      Obp28adel and Df(3R)Obp83-ab homozygous mutant adults do not have gross defects in the size, morphology or position of basiconic sensilla, compared to controls; mutant ab1 and ab2 sensilla have no difference in their responses to odorants, compared to controls.

      Obp28adel, Obp19adel and Df(3R)Obp83-ab homozygous mutant adults do not have gross defects in the size, morphology or position of basiconic sensilla, compared to controls; mutant ab3 sensilla have no difference in their responses to odorants, compared to controls.

      (Xiao et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Obp28a-
      (Xiao et al., 2019)
      Obp28adel
      Name Synonyms
      Secondary FlyBase IDs
        References (3)