FB2026_02 , released June 18, 2026
Allele: Dmel\Larp4BGS9719
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General Information
Symbol
Dmel\Larp4BGS9719
Species
D. melanogaster
Name
FlyBase ID
FBal0338168
Feature type
allele
Associated gene
Dmel\Larp4B
Associated Insertion(s)
P{GSV6}Larp4BGS9719
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV6}Larp4BGS9719
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV6}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of Larp4BGS9719 results in reduced size of larval wing discs (with Scer\GAL4vg.M.Exel) as well as adult eyes (with Scer\GAL4ey.3.5.Exel or Scer\GAL4GMR.PU) or wings (with Scer\GAL4sd.PU) and an increase in cell death is observed in larval eye disc (with Scer\GAL4GMR.PU). Additionally, Scer\GAL4ppl.PP-driven expression of Larp4BGS9719 leads to decreased cell size of fat body cells in third instar larvae.

        (Funakoshi et al., 2018)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The reduced size of eyes and wings observed in adult flies expressing Larp4BGS9719 under the control of Scer\GAL4ey.3.5.Exel or Scer\GAL4sd.PU, respectively, along with the decreased cell size of larval fat body cells (with the Scer\GAL4ppl.PP driver) is suppressed by co-expression of MycScer\UAS.cZa.

        (Funakoshi et al., 2018)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Larp4BGS9719
        larp4BGS9719
        (Funakoshi et al., 2018)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)