FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sdkΔ15
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General Information
Symbol
Dmel\sdkΔ15
Species
D. melanogaster
Name
FlyBase ID
FBal0340184
Feature type
allele
Associated gene
Dmel\sdk
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Malin et al., 2022, Astigarraga et al., 2018)
Mutagen
P-element activity
(Astigarraga et al., 2018)
Progenitor genotype
P{EP}sdkEP369
(Astigarraga et al., 2018)
Cytology
Description

Imprecise excision of P{EP}sdkEP369 results in a deletion of 1240bp at the 5' end of sdk.

(Astigarraga et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In sdkΔ15 pupal retina, intercalation (visualized by &agr-catenin-GFP) is often incomplete while the number of secondary pigment cells in most lattice edges does not change when compared to controls.

      (Letizia et al., 2019)

      sdkΔ15 homozygous adults show too many or too few R1-R6 photoreceptors in a small but significant proportion of ommatidia, as compared to controls.

      (Astigarraga et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sdkdelta15
      (Isasti-Sanchez et al., 2021)
      sdkΔ15
      (Gandhi et al., 2025, Malin et al., 2022, Letizia et al., 2019, Astigarraga et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)