FlyBase Allele Report: Dmel\aqz[KG08159]

General Information

Symbol

Dmel\aqz^KG08159

Species

D. melanogaster

Name

FlyBase ID

FBal0340384

Feature type

allele

Associated gene

Dmel\aqz

Associated Insertion(s)

P{SUPor-P}aqz^KG08159

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele

Mutagen

Nature of the Allele

Allele class

hypomorphic allele

(Mendoza-Ortíz et al., 2018)

Mutagen

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}aqz^KG08159

Cytology

Description

Insertion in the aqz promoter.

(Mendoza-Ortíz et al., 2018)

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:8,820,700..8,820,700 [-]

(Mendoza-Ortíz et al., 2018)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

embryonic/larval segmentation phenotype

(Mendoza-Ortíz et al., 2018)

neurogenic phenotype | recessive

(Mendoza-Ortíz et al., 2018)

viable (with aqz¹)

(Mendoza-Ortíz et al., 2018)

viable (with aqz^CB03335)

(Mendoza-Ortíz et al., 2018)

viable (with Df(3R)BSC478)

(Mendoza-Ortíz et al., 2018)

viable (with Df(3R)BSC506)

(Mendoza-Ortíz et al., 2018)

viable (with Df(3R)Exel6150)

(Mendoza-Ortíz et al., 2018)

viable | recessive

(Mendoza-Ortíz et al., 2018)

Phenotype Manifest In

embryonic/larval cuticle

(Mendoza-Ortíz et al., 2018)

larval central nervous system

(Mendoza-Ortíz et al., 2018)

Detailed Description

Statement

Reference

aqz^KG08159 homozygous embryos show prevalent central and peripheral nervous system defects, cuticle defects (e.g. cuticle holes), and patterning defects, as compared to controls.

(Mendoza-Ortíz et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

14691

y¹ w^67c23; P{SUPor-P}aqz^KG08159 ry⁵⁰⁶

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

aqz²

(Mendoza-Ortíz et al., 2018)

aqz^KG08159

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close