FB2026_03 , released September 17, 2026
Allele: Avic\GFPEGFP.βTub85D.Tag:PH(hPLCD1)
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General Information
Symbol
Avic\GFPEGFP.βTub85D.Tag:PH(hPLCD1)
Species
A. victoria
Name
FlyBase ID
FBal0340408
Feature type
allele
Associated gene
Avic\GFP
Associated Insertion(s)
Carried in Construct
P{βTub85D-PLCD1.GFP}
Also Known As
PLCδ-PH-GFP, PLCδ-PH::GFP
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Wong, 2005)
Progenitor genotype
Carried in construct
P{βTub85D-PLCD1.GFP}
Cytology
Description

A βTub85D promoter drives expression of a fluorescent reporter of phosphatidylinositol 4,5 bisphosphate (PIP2) distribution (composed of EGFP fused to Tag:PH(hPLCD1)).

(Wong, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
βTub85D
Encoded product / tool
EGFP
Tagged with
Tag:PH(hPLCD1)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      spermatid & nucleus | supernumerary

      (Wong, 2005)
      Detailed Description
      Statement
      Reference

      Expression of the Hsap\PLCD1βTub85D.T:Avic\GFP-EGFP transgene causes a dramatic cytokinesis defect, with 47.8-72% of spermatids containing multiple nuclei. The majority of the multinucleate cells contain three or four nuclei.

      (Wong, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Avic\GFPEGFP.βTub85D.Tag:PH(hPLCD1)
      Hsap\PLCD1βTub85D.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0189987
      • FBal0340333
      References (10)