FB2026_03 , released September 17, 2026
Allele: Dmel\Su(z)2Q105term-2
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General Information
Symbol
Dmel\Su(z)2Q105term-2
Species
D. melanogaster
Name
FlyBase ID
FBal0341792
Feature type
allele
Associated gene
Dmel\Su(z)2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Nguyen et al., 2017)
Progenitor genotype
Su(z)21
(Nguyen et al., 2017)
Cytology
Description

Also retains the original Su(z)21 mutation (stop codon at residue 284).

(Nguyen et al., 2017)

Amino acid replacement: Q105term.

(Nguyen et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:12,999,948..12,999,948 [+]
Nucleotide change:

C12999948T

Amino acid change:

Q105term | Su(z)2-PA; Q105term | Su(z)2-PB; Q105term | Su(z)2-PC

Reported amino acid change:

Q105term

Comment:

Line also retains the original Su(z)21 mutation (stop codon at residue 284). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Nguyen et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Although the Su(z)2Q105term-1 and Su(z)2Q105term-2 alleles both contain the same mutation (a stop codon at residue 105 in addition to the lesion of the progenitor Su(z)21 allele), they do not behave identically, suggesting that they may each be associated with other alterations either elsewhere within Su(z)2 (outside the region sequenced in FBrf0234676) or changes elsewhere in the genome.

      (Nguyen et al., 2017)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Q105*2
      (Nguyen et al., 2017)
      Su(z)2Q105term-2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)