FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL412xCRE
Open Close
General Information
Symbol
Scer\GAL412xCRE
Species
S. cerevisiae
Name
FlyBase ID
FBal0343237
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{12xCRE-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Yamazaki et al., 2018)
Progenitor genotype
Carried in construct
P{12xCRE-GAL4}
Cytology
Description

GAL4 is under the control of 12 cAMP response element (CRE, TGACGTCA) repeats, followed by a footprint 5 sequence (GCGCCGGCGCTTCCAG), a Hsp70 promoter and an SV40 terminator.

(Yamazaki et al., 2018)
Allele components
Component
Use(s)
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      gamma Kenyon cell | subset
      (Yamazaki et al., 2018)
      alpha/beta Kenyon cell | subset
      (Yamazaki et al., 2018)
      alpha'/beta' Kenyon cell | subset
      (Yamazaki et al., 2018)
      adult brain | restricted
      (Yamazaki et al., 2018)
      Additional Information
      Statement
      Reference

      ScerGAL412xCRE drives expression in approximately 350 gamma Kenyon cells, as well as small numbers of alpha/beta and alpha'/beta' Kenyon cells.

      (Yamazaki et al., 2018)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shits1.UAS.Tag:MYC at 31[o]C) of Scer\GAL412xCRE cells in adults during training, consolidation or retrieval significantly reduces 2 h aversive olfactory memory, compared to controls; reduced memory is not seen when inhibition is restricted to a smaller subset of Scer\GAL412xCRE cells using Scer\GAL80Mef2.mb247, Scer\GAL80R64D02 or Scer\GAL80R72B08.

      (Yamazaki et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL412xCRE
      Name Synonyms
      Secondary FlyBase IDs
        References (1)