FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\iPLA2-VIAΔ192
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General Information
Symbol
Dmel\iPLA2-VIAΔ192
Species
D. melanogaster
Name
FlyBase ID
FBal0343298
Feature type
allele
Associated gene
Dmel\iPLA2-VIA
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Lin et al., 2018)
Mutagen
P-element activity
(Lin et al., 2018)
Progenitor genotype
P{EPgy2}iPLA2-VIAEY05103
(Lin et al., 2018)
Cytology
Description

Deletion removing part of the iPLA2-VIA transcription unit. Generated by imprecise excision of P{EPgy2}iPLA2-VIAEY05103.

(Lin et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:9,863,722..9,864,639 [-]
Comment:

A 918bp deletion ( 3L:9863722..9864639 ) resulting from the imprecise excision of P{EPgy2}iPLA2-VIAEY05103 removes the 5' end of iPLA2-VIA. The sequence "GACCGTGCTCTGTGGAATCAGTGCTTAAAATCGAA" is inserted at the site of the deletion.

Inserted_sequence:

GACCGTGCTCTGTGGAATCAGTGCTTAAAATCGAA

(Lin and Bellen, 2019.2.8)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      iPLA2-VIAΔ174 mutants show lower performance in odor avoidance behavior (to 3-octanol or 4-methylcyclohexanol). These mutants also show progressive decreases in electroretinogram amplitudes and in on-transients electroretinogram amplitude.

      (Lin et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      iPLA2-VIAΔ192 is rescued by iPLA2-VIA+CH322-150H21

      (Lin et al., 2018)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      iPLA2-VIADelta192
      (Penfield and Montell, 2023)
      iPLA2-VIAΔ192
      (Lin et al., 2018)
      iPLA2-VIAΔ192
      (Lin and Bellen, 2019.2.8)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)