FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sod1null
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General Information
Symbol
Dmel\Sod1null
Species
D. melanogaster
Name
FlyBase ID
FBal0343866
Feature type
allele
Associated gene
Dmel\Sod1
Associated Insertion(s)
TI{TI}Sod1null
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Şahin et al., 2017)
Mutagen
CRISPR/Cas9
(Şahin et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{TI}Sod1null
Cytology
Description

The entire Sod1 open reading frame has been deleted, and replaced with a targeting sequence cassette in which a pair of inverted attP sites surround a loxP cassette that contains a Avic\GFP3xP3.cUa marker.

(Agudelo et al., 2020)

The complete Sod1 ORF is deleted.

(Şahin et al., 2017)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:11,112,198..11,114,063 [-]
Comment:

The entire Sod1 open reading frame has been deleted, and replaced with a targeting sequence cassette in which a pair of inverted attP sites surround a loxP cassette that contains a Avic\GFP3xP3.cUa marker.

(Agudelo et al., 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  amyotrophic lateral sclerosis type 1
      CEA
      (Agudelo et al., 2020)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Sod121
      (Ueda et al., 2021)
      Sod1null
      dsod1null
      (Agudelo et al., 2020)
      dsodnull21
      (Şahin et al., 2017)
      dsodnull26
      (Şahin et al., 2017)
      dsodnull
      (Şahin et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)