FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E2f1bmut
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General Information
Symbol
Dmel\E2f1bmut
Species
D. melanogaster
Name
FlyBase ID
FBal0343971
Feature type
allele
Associated gene
Dmel\E2f1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Kim et al., 2018)
gene targeting by homologous recombination
(Kim et al., 2018)
Progenitor genotype
Cytology
Description

The exon specific to the 'b' isoform (and its surrounding splice acceptor and donor sites) has been removed.

(Kim et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:21,624,243..21,624,294 [-]
Comment:

The exon specific to the 'b' isoform (and its surrounding splice acceptor and donor sites) has been removed. A four base footprint produced by PiggyBac transposition (ttaa) is left in its place.

Inserted_sequence:

TTAA

(Kim et al., 2018)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The variable nuclear size observed in the larval fat body of E2f1bmut/Df(3R)Exel6186 transheterozygotes is suppressible by the expression of CycEVDRC.cUa under the combine control of Scer\GAL4hs.PU and heat shock.

      (Kim et al., 2018)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      E2f1bmut
      Name Synonyms
      Secondary FlyBase IDs
        References (1)