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General Information
Symbol
Dmel\CCHa1SK8
Species
D. melanogaster
Name
FlyBase ID
FBal0344089
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

Deletion of 13bp within the CCHa1 coding sequence results in a frameshift and early translation termination after the addition of 11 novel amino acids.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion of 13bp within CCHa1 results in a frameshift.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

CCHa1SK8 mutant adult males have significantly reduced overall locomotor activity under normal light-dark (LD) conditions, or in continuous darkness (DD), compared to controls; under LD conditions, the morning activity period is shortened and there is a significantly longer inactive period between morning and evening peaks, compared to controls; under DD conditions, there is a significant reduction in morning activity and a phase delay in the mean acrophase, compared to controls, with no significant effect on free-running period.

CCHa1SK4/CCHa1SK8, CCHa1SK8/CCHa1SK8 and CCHa1SK8/+ animals do not exhibit any changes in pupariation time when compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)