FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TpiTag:HA
Open Close
General Information
Symbol
Dmel\TpiTag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0345100
Feature type
allele
Associated gene
Dmel\Tpi
Associated Insertion(s)
Carried in Construct
P{HA-Tpi}
Key Links
Transgenic product class
genomic_DNA
(Ma et al., 2018)
wild_type
(Ma et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Ma et al., 2018)
wild_type
(Ma et al., 2018)
Mutagen
in vitro construct
(Ma et al., 2018)
Progenitor genotype
Carried in construct
P{HA-Tpi}
Cytology
Description

Genomic fragment encompassing Tpi (extends from 1.4kb 5' of the transcription start to 1.1kb 3' of the transcription stop). The coding sequence is tagged at the N-terminal end with Tag:HA.

(Ma et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
Tpi
Encoded product / tool
Tpi
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults bearing one copy of TpiTag:HA show an increase in climbing ability in old/30-days adults but not in young/3-days adults, as compared to age-matched controls.

      (Ma et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      TpiTag:HA has long lived | dominant phenotype, enhanceable by Pgi[+]/PgiTag:HA

      (Ma et al., 2018)
      Enhancer of
      Statement
      Reference

      TpiTag:HA/Tpi[+] is an enhancer of long lived | dominant phenotype of PgiTag:HA

      (Ma et al., 2018)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TpiTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)