FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rab2Tag:HA
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General Information
Symbol
Dmel\Rab2Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0346044
Feature type
allele
Associated gene
Dmel\Rab2
Associated Insertion(s)
Carried in Construct
P{Rab2.HA}
Also Known As
HA-Rab2
Key Links
Transgenic product class
genomic_DNA
(Lund et al., 2018)
wild_type
(Lund et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Lund et al., 2018)
wild_type
(Lund et al., 2018)
Mutagen
in vitro construct
(Lund et al., 2018)
Progenitor genotype
Carried in construct
P{Rab2.HA}
Cytology
Description

Genomic fragment that encompasses Rab2, extending from 4.7kb upstream of the ATG start codon to approximately 1.0kb downstream of the transcriptional termination site. The coding sequence is tagged near the N-terminal end with Tag:HA; the tag is inserted downstream of the start Met and an intervening Gly residue, and is followed by a TSG linker.

(Lund et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
Rab2
Encoded product / tool
Rab2
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      organism | ubiquitous
      (Lund et al., 2018)
      imaginal disc

      Comment: enriched

      (Lund et al., 2018)
      larval central nervous system

      Comment: enriched

      (Lund et al., 2018)
      Additional Information
      Statement
      Reference

      The tagged Rab2 is ubiquitously expressed in third instar larvae with strong enrichment in the nervous system and imaginal discs.

      (Lund et al., 2018)
       
      Marker for
      Reflects expression of
      Rab2
      (Lund et al., 2018)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Rab2Tag:HA rescues Rab2Δ1

      (Lund et al., 2018)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Rab2Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)