FlyBase Allele Report: Dmel\Gr64a[UAS.cUa]

General Information

Symbol

Dmel\Gr64a^UAS.cUa

Species

D. melanogaster

Name

UAS construct a of Unknown

FlyBase ID

FBal0346601

Feature type

allele

Associated gene

Dmel\Gr64a

Associated Insertion(s)

Carried in Construct

P{UAS-Gr64a.U}

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Gr64a.U}

Cytology

Description

UAS regulatory sequences drive expression of Gr64a.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Gr64a

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^Gr61a.4.9/Gr64a^UAS.cUa is a suppressor | partially of abnormal neurophysiology | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9/Gr64a^UAS.cUa is a suppressor | partially of abnormal taste perception | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa, Gr64e^UAS.cUa is a suppressor | partially of abnormal neurophysiology | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa, Gr64e^UAS.cUa is a suppressor | partially of abnormal taste perception | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Gr61a.4.9, Gr64b^UAS.cUa, Gr64a^UAS.cUa is a non-suppressor of abnormal neurophysiology | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64b^UAS.cUa, Gr64a^UAS.cUa is a non-suppressor of abnormal taste perception | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Gr64d^UAS.cUa, Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa is a non-suppressor of abnormal neurophysiology | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Gr64d^UAS.cUa, Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa is a non-suppressor of abnormal taste perception | adult stage phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^Gr61a.4.9/Gr64a^UAS.cUa is a suppressor | partially of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5v phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa, Gr64e^UAS.cUa is a suppressor | partially of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5b phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Gr61a.4.9, Gr64b^UAS.cUa, Gr64a^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5b phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64b^UAS.cUa, Gr64a^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5v phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Gr64d^UAS.cUa, Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5b phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Gr64d^UAS.cUa, Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5v phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9/Gr64a^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5b phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Scer\GAL4^Gr61a.4.9, Gr64a^UAS.cUa, Gr64e^UAS.cUa is a non-suppressor of sugar-sensing neuron of prothoracic leg tarsal taste bristle 5v phenotype of Df(3L)ΔGr64, Gr5a^LEXA, Gr61a¹

(Yavuz et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Gr5a^LEXA, Gr61a¹, Df(3L)ΔGr64 triple homozygotes that also bear P{t15.3.R1} (P{t15.3.R1} rescues the lethality of Df(3L)ΔGr64 homozygosity) have impaired responsiveness to sweet chemical: sweet taste 5b sensilla GRNs virtually lack the expected responsiveness to the chemicals Sucrose, Fructose, Maltose, Trehalose, Glucose, Melezitose, Arabinose and Glycerol, as compared to controls; sweet taste 5v sensilla GRNs show the expected responsive only to Sucrose and Fructose, but lack responses to Maltose, Trehalose and Glucose.

Expressing Gr64a^UAS.cUa under the control of Scer\GAL4^Gr61a.4.9 restores the response of 5v sensilla GRNs only to Maltose but does not affect the responses of 5b sensilla GRNs.

Co-expressing Gr64a^UAS.cUa and Gr64e^UAS.cUa under the control of Scer\GAL4^Gr61a.4.9 restores the response of 5b sensilla GRNs only to Maltose and Sucrose, but does not affect the responses by 5v sensilla GRNs.

(Yavuz et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gr64a^UAS.cUa

Name Synonyms

UAS construct a of Unknown

Secondary FlyBase IDs

References (2)

Report Sections

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