FlyBase Allele Report: Dmel\Drs[R1]

General Information

Symbol

Dmel\Drs^R1

Species

D. melanogaster

Name

FlyBase ID

FBal0346806

Feature type

allele

Associated gene

Dmel\Drs

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

gene targeting by homologous recombination

Nature of the Allele

Allele class

Mutagen

gene targeting by homologous recombination

(Hanson et al., 2019)

Progenitor genotype

Cytology

Description

Non-synonymous nucleotide substitutions within Drs.

(Hanson et al., 2019)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3L:3,369,619..3,369,635 [+]

Comment:

17 bases (ATGATGCAGATCAAGTA) are substituted with 17 bases (GCTAGCACATATGCAGG).

Inserted_sequence:

GCTAGCACATATGCAGG

(Hanson et al., 2019)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Drs^R1 is a suppressor of abnormal stress response | adult stage phenotype of Mtk^R1

(Swanson et al., 2020)

Other

Statement

Reference

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Df(3R)ΔCecA-C, Drs^R1, Mtk^R1 has abnormal immune response | adult stage phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Df(3R)ΔCecA-C, Drs^R1, Mtk^R1 has visible | adult stage phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Df(3R)ΔCecA-C, Drs^R1, Mtk^R1 has increased mortality | conditional phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Drs^R1, Mtk^R1 has abnormal immune response | adult stage phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Drs^R1, Mtk^R1 has visible | adult stage phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Drs^R1, Mtk^R1 has increased mortality | conditional phenotype

(Hanson et al., 2023)

Phenotype Manifest In

Other

Statement

Reference

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Df(3R)ΔCecA-C, Drs^R1, Mtk^R1 has adult abdomen | conditional phenotype

(Hanson et al., 2023)

AttC^MB05438, AttD^SK1, Def^SK3, Df(2R)Dpt-SK1, Df(2R)Dro-AttAB-SK2, Drs^R1, Mtk^R1 has adult abdomen | conditional phenotype

(Hanson et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Drs r{w+}

(Nunes et al., 2021)

Drs^R1

(Rommelaere et al., 2024, Hanson et al., 2023, Carboni et al., 2022, Swanson et al., 2020, Hanson et al., 2019)

Drs^r(w+)

(Nunes et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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