FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tplus3bEGFP
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General Information
Symbol
Dmel\tplus3bEGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0347489
Feature type
allele
Associated gene
Dmel\tplus3b
Associated Insertion(s)
Carried in Construct
P{tplus3b.eGFP}
Key Links
Transgenic product class
wild_type
(Hundertmark et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hundertmark et al., 2019)
Mutagen
in vitro construct
(Hundertmark et al., 2019)
Progenitor genotype
Carried in construct
P{tplus3b.eGFP}
Cytology
Description

The tplus3b putative promoter region, 5'-UTR and open reading frame (ORF)is fused to EGFP at the C-terminus.

(Hundertmark et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
tplus3b
tplus3b_CG31703_tplus3b-eGFP
Encoded product / tool
tplus3b
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      spermatogenesis
      spermatocyte
      (Hundertmark et al., 2019)
      spermatid
      • nucleus

      Comment: round spermatids

      (Hundertmark et al., 2019)
      Additional Information
      Statement
      Reference

      Expression is observed in the nucleus and in the nucleolus in spermatocytes and in round spermatids.

      (Hundertmark et al., 2019)
       
      Marker for
      Reflects expression of
      tplus3b
      (Hundertmark et al., 2019)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      tplus3bEGFP is a suppressor of male sterile phenotype of tplus3aΔ, tplus3bΔ

      (Hundertmark et al., 2019)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      tplus3aΔ, tplus3bΔ double homozygotes are male sterile; this phenotype is rescued by tplus3bEGFP.

      (Hundertmark et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tplus3bEGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)