FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Glyp3-13
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General Information
Symbol
Dmel\Glyp3-13
Species
D. melanogaster
Name
FlyBase ID
FBal0348129
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Cytology
Description

1710bp deletion that removes the entire first exon of GlyP, including the transcriptional and translational start sites. Generated by imprecise excision of P{lacW}GlyPk07918.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

1710bp deletion resulting from the imprecise excision of P{lacW}GlyPk07918 that removes the entire first exon of GlyP, including the transcriptional and translational start sites.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

GlyP3-13 homozygous adults do not show obvious morphological defects, despite a small but significant decrease in body mass only in males. GlyP3-13/Df(2L)ED119 transheterozygous male and female adults also show a small but significant decrease in adult body mass.

GlyP3-13 homozygous adult males show a significant decrease in climbing ability only under starved conditions, but do not show significant defects in flight ability, as compared to controls. GlyP3-13/Df(2L)ED119 transheterozygous adult males do show significant changes in climbing ability, as compared to controls.

GlyP3-13 homozygotes show significant mortality during the larval stages, which is not related to molting defects, as evidenced by the completion of molting from the late second to third instar. Body size is normal at 24h and 48h after larval hatching (i.e. late first instar and late second instar, respectively), but is significantly smaller than controls both at 72h after larval hatching (i.e. mid-third instar) and, although less severe, at pupariation; the are no changes in developmental time to pupariation; third instar larvae food consumption is comparable to controls.

Embryos laid by GlyP3-13 mothers exhibit a delay in hatching and a slight decreased in hatching rate, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)