FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Daao1ko
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General Information
Symbol
Dmel\Daao1ko
Species
D. melanogaster
Name
FlyBase ID
FBal0349531
Feature type
allele
Associated gene
Dmel\Daao1
Associated Insertion(s)
Carried in Construct
Also Known As
CG12338ko
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Dai et al., 2019)
Mutagen
CRISPR/Cas9
(Dai et al., 2019)
Progenitor genotype
Cytology
Description

Most of the coding region (except the first 97 bp) of CG12338 is deleted ( 2R:10729640..10730764 , FB2018_02).

(Dai et al., 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:10,729,640..10,730,764 [-]
Comment:

Most of the Daao1 coding region (except the first 97 bp) is deleted ( 2R:10729640..10730764 , R6).

(Dai et al., 2019)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Daao1ko, Daao2ko double mutants show increased sleep during day-time and night-time, with decreased light pulse-induced arousal during night-time.

      (Dai et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Daao1ko is a suppressor of decreased sleep phenotype of Daao2ko

      (Dai et al., 2019)
      NOT Suppressor of
      Statement
      Reference

      Daao1ko/Daao2ko is a non-suppressor of decreased sleep phenotype of Nmdar1KO-Gal4

      (Dai et al., 2019)
      Other
      Statement
      Reference

      Daao1ko, Daao2ko has increased sleep phenotype

      (Dai et al., 2019)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG12338ko
      CG12338ko
      (Zheng et al., 2025, Dai et al., 2019)
      Daao1ko
      Name Synonyms
      Secondary FlyBase IDs
        References (2)