FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\poloΔUSE.GFP
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General Information
Symbol
Dmel\poloΔUSE.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0353107
Feature type
allele
Associated gene
Dmel\polo
Associated Insertion(s)
Carried in Construct
P{GFP-polo.ΔUSE}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Oliveira et al., 2019)
Progenitor genotype
Carried in construct
P{GFP-polo.ΔUSE}
Cytology
Description

Contains the polo gene in which the 28bp long upstream sequence element (USE) normally found in the 3'UTR has been deleted. The coding sequence is tagged at the N-terminal end with GFP.

(Oliveira et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
polo
Encoded product / tool
polo
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      poloΔUSE.GFP expressing poloS025604 homozygous adults exhibit malformation of the abdominal epidermis and tergite defects compared to controls.

      poloΔUSE.GFP expressing poloS025604 homozygous third instar larval mitotic neuroblasts exhibit an abnormal number of chromosomes compared to controls.

      (Oliveira et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      poloΔUSE.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)