FlyBase Allele Report: Scer\TOM70::Scer\UBC6[UAS.GFP]

General Information

Symbol

Scer\TOM70::Scer\UBC6^UAS.GFP

Species

S. cerevisiae

Name

FlyBase ID

FBal0355262

Feature type

allele

Associated gene

Scer\TOM70::Scer\UBC6

Associated Insertion(s)

Carried in Construct

PBac{UAS-ChiMERA.V}

Also Known As

UAS-ChiMERA

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Valadas et al., 2018)

Progenitor genotype

Carried in construct

PBac{UAS-ChiMERA.V}

Cytology

Description

UAS regulatory sequences drive expression of Scer\TOM70 fused to Scer\UBC6 and tagged with GFP; expression drives ER-mitochondrial contact formation (see PMID:19556461).

(Valadas et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Scer\TOM70::Scer\UBC6

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a suppressor | partially of bang sensitive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

NOT Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of abnormal neuroanatomy | adult stage | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of decreased cell number | adult stage | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of dopaminergic PPL1 neuron | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of dopaminergic PPM1 neuron | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of dopaminergic PPM2 neuron | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Scer\GAL4^elav-C155/Scer\TOM70::Scer\UBC6^UAS.GFP is a non-suppressor of dopaminergic PPM3 neuron | progressive phenotype of iPLA2-VIA^null

(Mori et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\TOM70::Scer\UBC6^UAS.GFP

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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