FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\doshs.2sev.cHa
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General Information
Symbol
Dmel\doshs.2sev.cHa
Species
D. melanogaster
Name
FlyBase ID
FBal0355310
Feature type
allele
Associated gene
Dmel\dos
Associated Insertion(s)
Carried in Construct
P{sE-dos.H}
Key Links
Transgenic product class
cDNA
(Herbst et al., 1999)
wild_type
(Herbst et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Herbst et al., 1999)
wild_type
(Herbst et al., 1999)
Mutagen
in vitro construct
(Herbst et al., 1999)
Progenitor genotype
Carried in construct
P{sE-dos.H}
Cytology
Description

A duplicated sev enhancer and Hsp70 promoter drive expression of a wild-type dos cDNA.

(Herbst et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
dos
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying two copies of this transgene generally have wild-type eyes, though on occasion slightly rough eyes can be seen, where it appears that the R7 photoreceptor cell has been transformed into a R1-R6 class photoreceptor cell.

      (Herbst et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      doshs.2sev.cHa is an enhancer of eye phenotype of sevS11.Tag:MYC

      (Herbst et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      doshs.2sev.cHa partially rescues dos1.46/dos2.42

      (Herbst et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      doshs.2sev.cHa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)