FB2026_02 , released June 18, 2026
Allele: Dmel\Trhn01
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General Information
Symbol
Dmel\Trhn01
Species
D. melanogaster
Name
FlyBase ID
FBal0357032
Feature type
allele
Associated gene
Dmel\Trhn
Associated Insertion(s)
Carried in Construct
Also Known As
Trh01
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Qian et al., 2017)
Mutagen
CRISPR/Cas9
(Qian et al., 2017)
Progenitor genotype
Cytology
Description

Two basepairs within Trh are deleted, causing an early translational stop.

(Qian et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:1,191,505..1,191,506 [-]
Comment:

2bp in the Trh coding region at aa 366 are deleted leading to a frameshift and early translation termination.

(Qian et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  autism spectrum disorder
      CEA
      (Cao et al., 2022)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Trh01
      (Lv et al., 2024, Karki et al., 2023, Cao et al., 2022, Qian et al., 2017)
      Trhn01
      Name Synonyms
      Secondary FlyBase IDs
        References (4)