FlyBase Gene Report: Dmel\Trhn

wandering third instar larval stage

(Neckameyer et al., 2007)

Additional Descriptive Data

Trh is expressed in approximately 12 neuronal cell bodies lying between the optic lobe and the protocerebrum of each hemisphere. Two of these are LP1 neurons and occupy a position between the lobula and the inferior lateral protocerebrum. Approximately sixty cells of the protocerebrum are immunopositive for Trh. Approximately three SP1 neurons, four SP2 neurons, and five IP neurons are Trh immunopositive. Two Trh immunopositive neurons of a small diameter are located in the posterior lateral protocerebrum, two in the superior lateral protocerebrum, two in the anterior lateral protocerebrum, and a single cell body in between the ventrolateral protocerebrum and the antennal lobe. Approximately 40 amacrine neurons, situated above the protocerebrum and close to the protocerebral perineurium, two SE1 neurons, and three SE3 neurons are Trh immunopositive.

(Bao et al., 2010)

Trh is expressed ubiquitously in early embryos. Expression is not detected again until late embryogenesis when it is detected in a discrete subset of cells within the CNS. Expression is restricted to dopaminergic neurons.

(Neckameyer et al., 2007)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: P{GMR14G10-GAL4}

Stage

Tissue/Position (including subcellular localization)

Reference

Reporter: P{Trhn-GAL4.B}

Stage

Tissue/Position (including subcellular localization)

Reference

(Sadaf et al., 2012)

(Sadaf et al., 2012)

serotonergic neuron | subset of adult brain

(Riemensperger et al., 2013)

Reporter: P{Trhn-GAL4.long}

Stage

Tissue/Position (including subcellular localization)

Reference

(Burgos et al., 2018)

adult serotonergic LP2 neuron

(Alekseyenko et al., 2010)

FMRFamide SE2 neuron

(Alekseyenko et al., 2010)

adult protocerebrum | restricted

(Alekseyenko et al., 2010)

posterior lateral protocerebrum | restricted

(Alekseyenko et al., 2010)

adult serotonergic SEM neuron

(Xu et al., 2016, Alekseyenko et al., 2010)

adult serotonergic SE1 neuron

(Xu et al., 2016, Alekseyenko et al., 2010)

adult brain | restricted

(Xu et al., 2016)

adult serotonergic PMPD neuron

(Xu et al., 2016)

adult serotonergic PMPM neuron | subset

(Xu et al., 2016)

adult serotonergic IP neuron | subset

(Xu et al., 2016)

adult serotonergic PLP neuron

(Xu et al., 2016)

adult serotonergic LP2 neuron | subset

(Xu et al., 2016)

adult serotonergic LP3 neuron | subset

(Xu et al., 2016)

adult serotonergic SE2 neuron

(Xu et al., 2016)

adult serotonergic ALP neuron | subset

(Xu et al., 2016)

adult serotonergic T1 neuron | subset

(Xu et al., 2016)

adult serotonergic T2 neuron | subset

(Xu et al., 2016)

adult serotonergic T3 neuron | subset

(Xu et al., 2016)

serotonergic neuron | subset of adult abdomen

(Xu et al., 2016)

adult serotonergic ADMP neuron

(Xu et al., 2016)

serotonergic IP1 neuron 1

(Xu et al., 2016)

Reporter: P{Trhn-GAL4.S}

Stage

Tissue/Position (including subcellular localization)

Reference

(Shearin et al., 2013)

interneuron | subset

(Shearin et al., 2013)

Reporter: P{Trhn-GAL4.U}

Stage

Tissue/Position (including subcellular localization)

Reference

medulla non-directional M6 local neuron 7

(Chin et al., 2014)

Reporter: P{Trhn-lexA::p65}

Stage

Tissue/Position (including subcellular localization)

Reference

interneuron | subset

(Otto et al., 2018, Shearin et al., 2013)

(Shearin et al., 2013)

Reporter: PBac{Trhn-lexA.R}

Stage

Tissue/Position (including subcellular localization)

Reference

(Albin et al., 2015)

Reporter: PBac{Trhn-QF.S} P{Trhn-QF.S}

Stage

Tissue/Position (including subcellular localization)

Reference

(Shearin et al., 2013)

interneuron | subset

(Shearin et al., 2013)

Reporter: TI{2A-lexA::p65}Trhn^2A-lexA

Stage

Tissue/Position (including subcellular localization)

Reference