FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Efa6GX6w+
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General Information
Symbol
Dmel\Efa6GX6w+
Species
D. melanogaster
Name
FlyBase ID
FBal0357073
Feature type
allele
Associated gene
Dmel\Efa6
Associated Insertion(s)
TI{TI}Efa6GX6w+
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-out gene targeting
(Huang et al., 2009)
Progenitor genotype
Associated Insertion(s)
TI{TI}Efa6GX6w+
Cytology
Description

Most of the Efa6 coding region has been deleted. A 50bp version of the attP site and a loxP cassette containing a w+* marker are present in place of the deleted sequence.

(Huang et al., 2009)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:22,598,356..22,605,777 [+]
Comment:

Most of the Efa6 coding region has been deleted. A 50bp version of the attP site and a loxP cassette containing a w+* marker are present in place of the deleted sequence. The deletion was reported to map to 3R:18 ,424,078..18,431,499 in release 5 coordinates.

(Huang et al., 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cultured neurons from stage 11 Efa6GX6w+ embryos show a small but significant increase in axon length, as compared to controls. Growth cone filopodia seem to have more and more stable microtubules (increased number of microtubules, and longer EB1 comet lifetime), as compared to controls. The axon shaft shows significantly more filopodia with microtubules, as compared to controls.

      (Qu et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG31158GX6
      (Huang et al., 2009)
      Efa6GX6[w+]
      (Qu et al., 2019)
      Efa6GX6w+
      Name Synonyms
      Secondary FlyBase IDs
        References (2)