Fam92¹ homozygotes and Fam92¹/Df(2L)Exel6033 transheterozygotes show impaired geotaxis response in bang assays compared to Fam92¹ heterozygous controls, as only a few files reach the top of the tube after 30s. They also show severely reduced male fertility.

The chordotonal neurons of Fam92¹ homozygous scolopidia occasionally show fewer cilia and axonemal structure defects such as lack of microtubule doublets, excess accumulation of dense material beneath the ciliary membrane and deformation of the membrane. Most transitional zones show normal ultrastructure, but a few show incomplete radial symmetry and accumulate material (as observed for cilia). Linkers connecting the axoneme to the membrane can still be observed.

Fam92¹ testes showed a moderate dispersion of the nuclei along cysts and altered migration of sperm individualization complexes. Round spermatids exhibit axonemal defects, including missing microtubule central pairs and/or doublets, broken symmetry with each part of the axoneme being relocated along the mitochondria, or missing axonemes; some spermatids also exhibit aberrant growth of axonemal microtubules. Fam92¹ spermatocytes exhibit some undocked centrioles, as well as irregular distal end or microtubules extending from the centriole tip.