FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\snoRNA:2R:9445410UAS.cSa
Open Close
General Information
Symbol
Dmel\snoRNA:2R:9445410UAS.cSa
Species
D. melanogaster
Name
UAS construct a of Soule
FlyBase ID
FBal0359001
Feature type
allele
Associated gene
Dmel\snoRNA:2R:9445410
Associated Insertion(s)
Carried in Construct
PBac{UAS-snoRNA:2R:9445410.S}
Key Links
Transgenic product class
wild_type
(Soulé et al., 2020)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Soulé et al., 2020)
Mutagen
in vitro construct
(Soulé et al., 2020)
Progenitor genotype
Carried in construct
PBac{UAS-snoRNA:2R:9445410.S}
Cytology
Description

UAS regulates expression of the 157 bp snoRNA:2R:9445410 gene.

(Soulé et al., 2020)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
snoRNA:2R:9445410
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Constitutive expression of snoRNA:2R:9445410UAS.cSa under the control of Scer\GAL4NP0001 does not rescue the decreased lifespan of Df(2R)F4 homozygous females. In fact, adulthood-only expression under the control of Scer\GAL4mex1.GS (induced by feeding with RU486) enhances the decreased lifespan of Df(2R)F4 homozygous females.

      (Soulé et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Df(2R)F4, Scer\GAL4mex1.GS, snoRNA:2R:9445410UAS.cSa has short lived | RU486 conditional phenotype

      (Soulé et al., 2020)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      snoRNA:2R:9445410UAS.cSa
      Name Synonyms
      UAS construct a of Soule
      Secondary FlyBase IDs
        References (1)