FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\5-HT2BPGF3
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General Information
Symbol
Dmel\5-HT2BPGF3
Species
D. melanogaster
Name
FlyBase ID
FBal0359121
Feature type
allele
Associated gene
Dmel\5-HT2B
Associated Insertion(s)
TI{2A-GAL4}5-HT2BPGF3
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Kondo et al., 2020)
gene targeting by homologous recombination
(Kondo et al., 2020)
Progenitor genotype
Associated Insertion(s)
TI{2A-GAL4}5-HT2BPGF3
Cytology
Description

A sequence cassette composed of an attP site, T2A-GAL4, a loxP site and an FRT3 site has been inserted into the 5-HT2B locus, at the C-terminal end of the open reading frame, resulting in the GAL4 driver being expressed as a separate protein under the control of the endogenous 5-HT2B sequences.

(Kondo et al., 2020)
Allele components
Component
Use(s)
Inserted element
TI{2A-GAL4}
Encoded product / tool
GAL4
Also carries
attP
FRT3
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      5-HT2BPGF3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)