FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4drl.442
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General Information
Symbol
Scer\GAL4drl.442
Species
S. cerevisiae
Name
FlyBase ID
FBal0360266
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{drl-GAL4.442}
Also Known As
TIFR-Gal4, 442-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Hitier et al., 2000)
Progenitor genotype
Carried in construct
P{drl-GAL4.442}
Cytology
Description

An approximately 1.5kb XbaI/SalI genomic fragment from the first exon of drl, regulates expression of a GAL4 driver.

(Hitier et al., 2000)
Allele components
Component
Use(s)
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      larval brain ensheathing glial cell
      (Lovick et al., 2017)
      P-stage
      transient interhemispheric fibrous ring
      (Lovick et al., 2017)
      adult stage
      ensheathing glial cell
      (Lee et al., 2019, Lu et al., 2014)
      Additional Information
      Statement
      Reference

      ScerGAL4TIFR drives expression in ensheathing glial cells.

      (Lee et al., 2019)

      During pupal stages, ScerGAL4drl.442 brain expression is restricted to an "interhemispheric ring" (TIFR).

      (Lovick et al., 2017)
       
      Marker for
      transient interhemispheric fibrous ring
      (Marmor-Kollet et al., 2019)
      Reflects expression of
      drl
      (Lovick et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4drl.442, drkKK109233 has glial cell phenotype, suppressible by SosJC2/Sos[+]

      (Lu et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Scer\GAL4442
      Scer\GAL4TIFR
      Scer\GAL4drl.442
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0298837
      • FBal0120637
      References (14)