FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4unc-4-DBD
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General Information
Symbol
Scer\GAL4unc-4-DBD
Species
S. cerevisiae
Name
FlyBase ID
FBal0360281
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
TI{2A-GAL4(DBD)::Zip-}unc-4DBD
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Lacin et al., 2020)
Progenitor genotype
TI{TI}unc-4FRT
(Lacin et al., 2020)
Associated Insertion(s)
TI{2A-GAL4(DBD)::Zip-}unc-4DBD
Cytology
Description

2A-GAL4(DBD)::Zip- is introduced into the attP site in the TI{TI}unc-4FRT progenitor. The Trojan insertion introduces a stop codon, truncating the unc-4 protein after its first exon.

(Lacin et al., 2020)
Allele components
Component
Use(s)
Inserted element
TI{2A-GAL4(DBD)::Zip-}
Regulatory region(s)
unc-4
Encoded product / tool
GAL4(DBD)::Zip-
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      Notch OFF hemilineage neuron of NB7-4 lineage neuron

      Comment: when combined with P{R77C10-p65.AD}

      (Lacin et al., 2020)
      sensory neuron of female genitalia

      Comment: when combined with P{Tub-dVP16AD.D}

      (Lacin et al., 2020)
      Notch ON hemilineage neuron of NB7-4 lineage neuron

      Comment: when combined with Mi{Trojan-p65AD.0}TfAP-2MI05213-Tp65AD.0

      (Lacin et al., 2020)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      unc-4
      (Lacin et al., 2020)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Hsim\VP16AD.Tub, unc-4UAS.cLa, Scer\GAL4unc-4-DBD partially rescues unc-4DBD

      (Lacin et al., 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Scer\GAL4unc-4-DBD
      unc-4DBD
      (Lacin et al., 2020)
      uncDBD
      (Lacin et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)