FlyBase Allele Report: Dmel\Inx2[RNAi.UAS.WIZ]

General Information

Symbol

Dmel\Inx2^RNAi.UAS.WIZ

Species

D. melanogaster

Name

FlyBase ID

FBal0361240

Feature type

allele

Associated gene

Dmel\Inx2

Associated Insertion(s)

Carried in Construct

P{UAS-Inx2.RNAi.WIZ}

Also Known As

inx2 RNAi

Key Links

Transgenic product class

RNAi_reagent

(Lechner et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Lechner et al., 2007)

Mutagen

in vitro construct

(Lechner et al., 2007)

Progenitor genotype

Carried in construct

P{UAS-Inx2.RNAi.WIZ}

Cytology

Description

UAS regulatory sequences drive expression of RNAi against Inx2 (tail-to-tail orientation of a 535bp fragment corresponding to nucleotides 323-857 of the cDNA).

(Lechner et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Inx2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased occurrence of cell division | larval stage, with Scer\GAL4^c311

(Richard et al., 2017)

decreased size | adult stage, with Scer\GAL4^c311

(Richard et al., 2017)

decreased size | adult stage, with Scer\GAL4^eya.PB

(Richard et al., 2017)

decreased size | adult stage, with Scer\GAL4^NP2631

(Richard et al., 2017)

visible | adult stage, with Scer\GAL4^c311

(Richard et al., 2017)

visible | adult stage, with Scer\GAL4^ey.200.Exel

(Richard et al., 2017)

visible | adult stage, with Scer\GAL4^eya.PB

(Richard et al., 2017)

visible | adult stage, with Scer\GAL4^NP2631

(Richard et al., 2017)

Phenotype Manifest In

eye, with Scer\GAL4^c311

(Richard et al., 2017)

eye, with Scer\GAL4^eya.PB

(Richard et al., 2017)

eye, with Scer\GAL4^NP2631

(Richard et al., 2017)

eye disc, with Scer\GAL4^c311

(Richard et al., 2017)

vibrissal bristle | absent | adult stage, with Scer\GAL4^ey.200.Exel

(Richard et al., 2017)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has decreased size | adult stage phenotype, non-suppressible by ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has visible | adult stage phenotype, non-suppressible by ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has decreased size | adult stage phenotype, non-suppressible by Inx3^UAS.cSa, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has visible | adult stage phenotype, non-suppressible by Inx3^UAS.cSa, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has decreased size | adult stage phenotype, non-suppressible by Inx3^UAS.cSa/ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has visible | adult stage phenotype, non-suppressible by Inx3^UAS.cSa/ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Other

Statement

Reference

Inx2^RNAi.UAS.WIZ, Inx3^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has visible | adult stage phenotype

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Inx3^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has decreased size | adult stage phenotype

(Richard et al., 2017)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has eye phenotype, non-suppressible by ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has eye phenotype, non-suppressible by Inx3^UAS.cSa, Scer\GAL4^eya.PB

(Richard et al., 2017)

Inx2^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has eye phenotype, non-suppressible by Inx3^UAS.cSa/ogre^UAS.Tag:MYC, Scer\GAL4^eya.PB

(Richard et al., 2017)

Other

Statement

Reference

Inx2^RNAi.UAS.WIZ, Inx3^RNAi.UAS.WIZ, Scer\GAL4^eya.PB has eye phenotype

(Richard et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

Inx2^RNAi.UAS.WIZ is partially rescued by Scer\GAL4^eya.PB/Inx2^UAS.Tag:MYC

(Richard et al., 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Inx2^RNAi.UAS.WIZ

Inx2^{dsRNA.UAS.WIZ}

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close