FlyBase Allele Report: Dmel\CaMKII[RNAi.UAS.cUa]

General Information

Symbol

Dmel\CaMKII^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0361633

Feature type

allele

Associated gene

Dmel\CaMKII

Associated Insertion(s)

Carried in Construct

P{UAS-CaMKII.RNAi.U}

Also Known As

UAS-CaMKII RNAi

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-CaMKII.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an RNAi line that targets CaMKII.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

CaMKII

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates neuromuscular disease

modeled by Hsap\TRPV4^R269C.UAS

(Woolums et al., 2020)

modeled by Hsap\TRPV4^UAS.cWa

(Woolums et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

CaMKII^RNAi.UAS.cUa, Scer\GAL4^CCAP.PU is a suppressor | partially of visible | adult stage phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^CCAP.PU

(Woolums et al., 2020)

Scer\GAL4^CCAP.PU/CaMKII^RNAi.UAS.cUa is a suppressor | partially of abnormal neuroanatomy | larval stage | progressive phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^ppk.PU

(Woolums et al., 2020)

CaMKII^RNAi.UAS.cUa, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of abnormal locomotor behavior | adult stage | progressive | RU486 conditional phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^{elav.Switch.PO}

(Woolums et al., 2020)

CaMKII^RNAi.UAS.cUa, Scer\GAL4^CCAP.PU is a suppressor | partially of abnormal neurophysiology | adult stage phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^CCAP.PU

(Woolums et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

CaMKII^RNAi.UAS.cUa, Scer\GAL4^CCAP.PU is a suppressor | partially of wing phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^CCAP.PU

(Woolums et al., 2020)

Scer\GAL4^CCAP.PU/CaMKII^RNAi.UAS.cUa is a suppressor | partially of larval multidendritic class IV neuron | wandering third instar larval stage phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^ppk.PU

(Woolums et al., 2020)

Scer\GAL4^CCAP.PU/CaMKII^RNAi.UAS.cUa is a suppressor | partially of axon | wandering third instar larval stage phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^ppk.PU

(Woolums et al., 2020)

CaMKII^RNAi.UAS.cUa, Scer\GAL4^CCAP.PU is a suppressor | partially of adult CCAP abdominal neuron phenotype of Hsap\TRPV4^R269C.UAS, Scer\GAL4^CCAP.PU

(Woolums et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CaMKII^RNAi.UAS.cUa

CaMKII^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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