FB2026_02 , released June 18, 2026
Allele: Dmel\Cbs8
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General Information
Symbol
Dmel\Cbs8
Species
D. melanogaster
Name
FlyBase ID
FBal0362607
Feature type
allele
Associated gene
Dmel\Cbs
Associated Insertion(s)
TI{TI}Cbs8
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Zatsepina et al., 2020)
Mutagen
CRISPR/Cas9
(Shilova et al., 2020, Zatsepina et al., 2020)
Progenitor genotype
Associated Insertion(s)
TI{TI}Cbs8
Cytology
Description

The Cbs gene has been replaced with a mCherry-expressing reporter.

(Zatsepina et al., 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
X:21,046,862..21,049,348 [+]
Comment:

The Cbs gene has been replaced with a mCherry-expressing reporter.

(Evgen'ev, 2020.11.5)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  homocystinuria
      CEA
      (Zatsepina et al., 2022)
      CEC with Cth1
      (Zatsepina et al., 2022)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CBS(8)
      (Shaposhnikov et al., 2022)
      Cbs8
      cbs8
      (Zatsepina et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)